RELUGOLIX INTERMEDIATE MANUFACTURING

Relugolix Intermediate Manufacturing

Relugolix Intermediate Manufacturing

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A.R. Life Science Pvt. Ltd.: Pioneers in Relugolix Intermediate Manufacturing
A.R. Life Science Pvt. Ltd., headquartered in Hyderabad, India, is a leading name in the pharmaceutical industry, known for its exceptional expertise in the production of Active Pharmaceutical Ingredients (APIs) and intermediates. Among their portfolio of high-quality intermediates is Relugolix Intermediate, with the chemical name 3-Amino-6-methoxypyridazine (CAS No. 7252-84-8).

This blog delves into the properties, mechanism of action, and therapeutic importance of 3-Amino-6-methoxypyridazine, a critical intermediate used in the production of Relugolix, a groundbreaking medication for hormone-sensitive conditions.

About 3-Amino-6-methoxypyridazine
Product Name: 3-Amino-6-methoxypyridazine
CAS No.: 7252-84-8
Molecular Formula: C5H7N3O
Molecular Weight: 125.13 g/mol
MDL No.: MFCD01646127
Purity/Specification: 98%
Storage Requirements: Store in a dark, sealed, and dry environment at temperatures between 2–8°C.
Chemical and Physical Properties
Appearance: Pale yellow to off-white crystalline powder
Solubility: Soluble in polar organic solvents such as methanol and dimethyl sulfoxide (DMSO)
Boiling Point: Not available
Melting Point: Approximately 120°C–130°C
These properties ensure the stability and effectiveness of the compound during its integration into pharmaceutical formulations.

Mechanism of Action and Therapeutic Applications
Role in Relugolix Production
3-Amino-6-methoxypyridazine is an essential intermediate in synthesising Relugolix, a gonadotropin-releasing hormone (GnRH) receptor antagonist. Relugolix works by suppressing the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), thereby reducing the production of sex hormones like testosterone and estrogen.

Therapeutic Uses of Relugolix
Relugolix, produced using 3-Amino-6-methoxypyridazine, is used to treat hormone-sensitive conditions such as:

Prostate Cancer: Relugolix is effective in managing advanced prostate cancer by reducing testosterone levels.
Uterine Fibroids: It alleviates symptoms such as heavy menstrual bleeding by reducing estrogen production.
Endometriosis: Relugolix helps manage pain and other symptoms associated with endometriosis.

Why A.R. Life Science Pvt. Ltd. is the Preferred Partner
1. Superior Quality Standards
A.R. Life Science delivers 3-Amino-6-methoxypyridazine with a purity of 98%, ensuring reliability in pharmaceutical manufacturing.

2. Cutting-Edge Technology
The company employs advanced technologies and stringent quality control measures, guaranteeing consistency and excellence in production.

3. Commitment to Innovation
With years of expertise, A.R. Life Science continuously invests in research and development to stay ahead in the competitive pharmaceutical landscape.

4. Sustainable Practices
Environmental responsibility is a core value, with the company adopting eco-friendly production methods to minimize its carbon footprint.

Conclusion
3-Amino-6-methoxypyridazine (CAS No. 7252-84-8) is a vital intermediate in the synthesis of Relugolix, a medication that has transformed the treatment of hormone-sensitive diseases. With its unmatched commitment to quality, innovation, and sustainability, A.R. Life Science Pvt. Ltd. has emerged as a trusted leader in the pharmaceutical sector.

By providing high-purity intermediates like 3-Amino-6-methoxypyridazine, A.R. Life Science continues to contribute to global healthcare, empowering pharmaceutical advancements that improve patient outcomes worldwide.

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